The Effect of Testosterone Replacement Therapy on Nonalcoholic Fatty Liver Disease in Older Hypogonadal Men.
Hae Seung LeeSang Hun HanRonald S SwerdloffYoungju PakMatthew J BudoffChristina WangPublished in: The Journal of clinical endocrinology and metabolism (2023)
Our study did not show improvement of NAFLD in older hypogonadal men after 12 months of T versus placebo treatment, as assessed by three clinical scores and liver CT for hepatic steatosis. Future studies with longer treatment duration and additional NAFLD diagnostic modalities as primary outcome are warranted.