Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure.

Mateusz Siedlinski Lorenzo Carnevale Xiaoguang Xu Daniela CarnevaleEvangelos EvangelouMark J CaulfieldPasquale Maffia Joanna Marguerite WardlawNilesh J SamaniMaciej Tomaszewski Giuseppe Lembo Michael V Holmes Tomasz J Guzik

Published in: European heart journal (2023)

Complementary MR and observational analyses identify brain structures associated with BP, which may be responsible for the adverse effects of hypertension on cognitive performance.

Keyphrases

blood pressure
cognitive impairment
resting state
white matter
high resolution
functional connectivity
hypertensive patients
heart rate
gene expression
genome wide
cerebral ischemia
magnetic resonance imaging
magnetic resonance
subarachnoid hemorrhage
mass spectrometry