Current or recent smoking is associated with more variable telomere length in prostate stromal cells and prostate cancer cells.

Corrine E JoshuSarah B PeskoeChristopher M HeaphyStacey A KenfieldLorelei A MucciEdward L GiovannucciMeir J StampferGhilsuk YoonThomas K LeeJessica L HicksAngelo M De MarzoAlan K MeekerElizabeth A Platz

Published in: The Prostate (2017)

Telomere variability in prostate cells may be one mechanism through which smoking influences poor prostate cancer outcomes.

Keyphrases

prostate cancer
radical prostatectomy
induced apoptosis
smoking cessation
cell cycle arrest
benign prostatic hyperplasia
endoplasmic reticulum stress
cell death
oxidative stress
signaling pathway
skeletal muscle