Plasma-based strategy for inhibiting Candida albicans growth and CaMCA1 gene expression in vitro and reducing fungal pathogenicity in a murine model of vulvovaginal candidiasis.

Fatemeh Ebrahimi-ShaghaghiSeyed-Mohammad AtyabiMehdi Razzaghi-Abyaneh

Published in: Medical mycology (2022)

CAP was successfully used to inhibit fungal growth and CaMCA1 gene expression in C. albicans. It caused morphological alterations in membranous structures of the yeast cells and finally led to the cell death. CAP meaningfully reduced C. albicans virulence and pathogenicity in a murine model of VVC.

Keyphrases

candida albicans
biofilm formation
gene expression
cell death
cell cycle arrest
dna methylation
induced apoptosis
cell wall
signaling pathway
staphylococcus aureus
pseudomonas aeruginosa
high resolution