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HTRA1 promotes EMT through the HDAC6/Ac-α-tubulin pathway in human GBM cells.

Wenbo ZhaoYibo WuShuai WangFeihu ZhaoWenyu LiuZhiyi XueLin ZhangJian WangMingzhi HanXingang LiBin Huang
Published in: CNS neuroscience & therapeutics (2024)
Our results indicate that HTRA1 promotes the proliferation and migration of GBM cells in vitro and in vivo, and thus may be a potential target for treatment in gliomas.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • endothelial cells
  • epithelial mesenchymal transition
  • cell death
  • high grade
  • signaling pathway
  • risk assessment
  • induced pluripotent stem cells
  • climate change
  • smoking cessation