HTRA1 promotes EMT through the HDAC6/Ac-α-tubulin pathway in human GBM cells.

Wenbo ZhaoYibo WuShuai WangFeihu ZhaoWenyu LiuZhiyi XueLin ZhangJian WangMingzhi Han Xingang Li Bin Huang

Published in: CNS neuroscience & therapeutics (2024)

Our results indicate that HTRA1 promotes the proliferation and migration of GBM cells in vitro and in vivo, and thus may be a potential target for treatment in gliomas.

Keyphrases

induced apoptosis
cell cycle arrest
endothelial cells
epithelial mesenchymal transition
cell death
high grade
signaling pathway
risk assessment
induced pluripotent stem cells
climate change
smoking cessation