The contribution of ketone bodies to glycolytic inhibition for the treatment of adult and pediatric glioblastoma.
Frederic A VallejoSumedh S ShahNicolas de CordobaWinston M WaltersJeffrey PrinceZiad KhatibRicardo J KomotarSteven VanniRegina M GrahamPublished in: Journal of neuro-oncology (2020)
Targeting the metabolic pathway of GBM via glycolytic inhibition in conjunction with ketogenic diet or exogenous ketone body supplementation warrants further investigation as a promising adjunctive treatment to conventional therapy.