Obesity correlates with the immunosuppressive ILC2s-MDSCs axis in advanced breast cancer.

Wei LiuBingyu LiDan LiuBing ZhaoGang SunJianbing Ding

Published in: Immunity, inflammation and disease (2024)

Conclusively, obesity may enhance the immunosuppressive effect of the ILC2-MDSC axis in advanced breast cancer. IL-5 may play a vital role in the ILC2-MDSC axis and obesity in TNBC.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
high fat diet induced
type diabetes
weight gain
nk cells
adipose tissue
skeletal muscle
physical activity