Post-transplant cyclophosphamide as sole GHVD prophylaxis after matched reduced-intensity conditioning allotransplant.
Amandine Le BourgeoisMaxime JullienAlice GarnierPierre PeterlinMarie C BénéThierry GuillaumePatrice ChevallierPublished in: Clinical and translational medicine (2023)
Despite paradoxically good survivals, especially GRFS, this study failed to demonstrate that PTCY (± ATG) alone can be used for Baltimore-based RIC PB Allo-HSCT with matched donors. Other combinations should be tested to try and avoid long-term use of immunosuppressive drugs following Allo-HSCT in this setting.