Emergence of tet(X2) in Acinetobacter pittii confers clinical resistance to tigecycline.
Changrui QianZhexiao MaLuozhu FengWenhui GuoYijia HanYi ZhangChunquan XuJianming CaoZhexiao MaPublished in: The Journal of antimicrobial chemotherapy (2023)
Our study demonstrates that tet(X2) is a determinant conferring clinical resistance to tigecycline in Acinetobacter species. The emergence of Tn7533 may lead to the potential dissemination of tigecycline and carbapenem resistance in Acinetobacter, which requires continuous monitoring.