Single-Cell Transcriptome Analysis of the Circle of Willis in a Mouse Cerebral Aneurysm Model.
Alejandra N MartinezGiovane G TorteloteCrissey L PascaleIsabella G McCormackKristen D NordhamNatalie J SuderMitchell W CouldwellAaron S DumontPublished in: Stroke (2022)
Our data identify CA disease-relevant transcriptional signatures of vascular cells in the CoW and is searchable via a web-based R/shiny interface.
Keyphrases
- single cell
- induced apoptosis
- cell cycle arrest
- coronary artery
- rna seq
- gene expression
- subarachnoid hemorrhage
- electronic health record
- transcription factor
- high throughput
- big data
- internal carotid artery
- endoplasmic reticulum stress
- oxidative stress
- cell death
- brain injury
- heat shock
- abdominal aortic aneurysm
- cerebral ischemia
- blood brain barrier
- data analysis
- middle cerebral artery