Enhanced production of taxadiene in Saccharomyces cerevisiae.
Behnaz NowrouziRachel A LiLaura E WallsLeo d'EspauxKoray MalcıLungang LiangNestor Jonguitud-BorregoAlbert I Lerma-EscaleraJose R Morones-RamirezJay D KeaslingLeonardo RiosPublished in: Microbial cell factories (2020)
The results of this study highlight the benefit of employing a combination of molecular biology and bioprocess tools during synthetic pathway development, with which TASY activity was successfully improved by 6.5-fold compared to the highest literature titre in S. cerevisiae cell factories.