Discrepancy between bone density and bone material strength index in three siblings with Camurati-Engelmann disease.
Sabina HerreraR SorianoX NoguésR Güerri-FernandezD GrinbergN García-GiraltN Martínez-GilS CastejónA González-LizaránS BalcellsA Diez-PerezPublished in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2017)
Despite strikingly increased BMD and normal microarchitecture, BMSi is affected in patients with CE. Microindentation could be an appropriate tool for assessing bone fragility in these patients. Bone disease in this group of patients requires further study to better understand the underlying regulatory mechanisms and their alterations.