Comparison of Germline versus Somatic BAP1 Mutations for Risk of Metastasis in Uveal Melanoma.

K G EwensE LalondeJ Richards-YutzC L ShieldsArupa Ganguly

Published in: BMC cancer (2018)

Defining germline vs. somatic nature of BAP1 mutations in UM can inform the individual about both the risk of metastasis, and the time to metastasis, which are critically important outcomes for the individual. This information can also change the cascade screening and surveillance of family members.

Keyphrases

dna repair
copy number
healthcare
type diabetes
metabolic syndrome
health information
adipose tissue
insulin resistance
skin cancer
clinical evaluation