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Novel insights into the pathophysiology of proliferative vitreoretinopathy: The role of vitreoschisis-induced vitreous cortex remnants.

Koen A van OverdamThierry P P van den BoschPeter G van EttenGurmit S UppalMarc VeckeneerRobert M Verdijk
Published in: Acta ophthalmologica (2022)
These findings confirm the role of VCR in preretinal PVR formation posterior to the vitreous base. We propose that the presence of VCR over the retinal surface should be qualified as a risk factor for PVR formation. Detection and adequate removal of VCR may improve the success rate of vitreoretinal surgeries.
Keyphrases
  • high glucose
  • optical coherence tomography
  • diabetic rats
  • diabetic retinopathy
  • loop mediated isothermal amplification
  • real time pcr
  • endothelial cells
  • oxidative stress