A novel phenotype-based drug-induced liver injury causality assessment tool (DILI-CAT) allows for signal confirmation in early drug development.

Richard P HermannDon C RockeyAyako SuzukiMichael MerzHans L Tillmann

Published in: Alimentary pharmacology & therapeutics (2022)

DILI-CAT, a clinically intuitive, data-driven, computer-assisted scoring algorithm, is a useful tool for early detection of drug's hepatotoxicity in clinical drug development.

Keyphrases

drug induced
adverse drug
machine learning