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Radiomics of high-resolution computed tomography for the differentiation between cholesteatoma and middle ear inflammation: effects of post-reconstruction methods in a dual-center study.

Christophe T ArendtDoris LeithnerMarius E MayerhoeferPeter GibbsChristian CzernyChristoph ArnoldnerIris BurckMartin LeinungYasemin TanyildiziLukas LengaSimon S MartinThomas J VoglRuediger E Schernthaner
Published in: European radiology (2020)
• Unenhanced high-resolution CT coupled with radiomics analysis may be useful for the differentiation between cholesteatoma and middle ear inflammation. • Pooling of data extracted from inhomogeneous CT datasets does not appear meaningful without further post-processing. • When using multi-centric CT data obtained with differences in acquisition parameters, post-reconstruction harmonization and data resampling clearly improve radiomics-based soft-tissue differentiation.
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