Determination of aortic stiffness using 4D flow cardiovascular magnetic resonance - a population-based study.
Andreas HarloffHanieh MirzaeeThomas LodemannPaul HagenlocherThomas WehrumJudith StuplichAnja HennemuthJürgen HennigSebastian GrundmannWerner VachPublished in: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance (2018)
4D flow CMR was successfully applied to calculate aortic PWV and thus aortic stiffness. Findings showed a high correlation with distensibility coefficients representing local compliance of the aorta. Our novel method and reference data for PWV may provide a reliable biomarker for the identification of patients with underlying cardiovascular disease and optimal guidance of future treatment in studies or clinical routine.
Keyphrases
- aortic valve
- pulmonary artery
- magnetic resonance
- cardiovascular disease
- aortic dissection
- left ventricular
- coronary artery
- pulmonary hypertension
- type diabetes
- electronic health record
- pulmonary arterial hypertension
- current status
- big data
- magnetic resonance imaging
- contrast enhanced
- combination therapy
- mass spectrometry
- coronary artery disease
- machine learning
- bioinformatics analysis
- solid phase extraction
- deep learning