Emerging Transcatheter Therapies for Valvular Heart Disease: Focus on Mitral and Tricuspid Valve Procedures.
Nikolaos KtenopoulosOdysseas KatsarosKonstantinos ToutouzasMaria DrakopoulouGrigorios G TsigkasConstantinos TsioufisPeriklis DavlourosKonstantinos ToutouzasAntonios KaranasosPublished in: Life (Basel, Switzerland) (2024)
The emergence of percutaneous treatment options provides novel therapeutic alternatives for older and feeble patients who are at high risk for any surgical procedure. The purpose of our review was to offer an up-to-date analysis of the rapidly expanding field of percutaneous technologies for mitral, tricuspid, and pulmonary procedures. Edge-to-edge repair is an established treatment for secondary mitral regurgitation (MR), while transcatheter mitral valve replacement is a potential and expanding option for managing both secondary and primary MR. However, additional advancements are necessary to enhance the safety and feasibility of this procedure. Transcatheter tricuspid intervention is an emerging option that was conceived after the success of transcatheter procedures in aortic and mitral valves, and it is currently still in the early stages of advancement. This can be attributed, at least in part, to the previously overlooked effect of tricuspid regurgitation on patient outcomes. The development of edge-to-edge repair represents the forefront of innovations in transcatheter procedures. There is a scarcity of data about tricuspid annuloplasty and replacement, and further study is necessary. Transcatheter mitral, tricuspid, and pulmonary procedures show prospects for the future, while their role in clinical practice has not been definitively established.
Keyphrases
- mitral valve
- aortic valve
- left atrial
- left ventricular
- aortic stenosis
- pulmonary hypertension
- ejection fraction
- minimally invasive
- clinical practice
- aortic valve replacement
- end stage renal disease
- newly diagnosed
- magnetic resonance imaging
- transcatheter aortic valve implantation
- prognostic factors
- atrial fibrillation
- current status
- machine learning
- heart failure
- ultrasound guided
- risk assessment
- big data
- pulmonary artery
- peritoneal dialysis
- combination therapy
- coronary artery disease
- middle aged
- climate change
- deep learning
- smoking cessation
- catheter ablation
- aortic dissection
- data analysis