Intraocular methotrexate for epithelial downgrowth: long-term outcomes in a multicentre case series.
Mélanie HébertRalph KyrillosMichael E SnyderRichard J MackoolJasmine H FrancisHelen K WuChristopher D RiemannMarie Eve LégaréPublished in: The British journal of ophthalmology (2022)
We report the largest case series of diffuse, sheet-like EDG treated with intraocular MTX with follow-ups up to 10 years. Intraocular MTX may be used effectively to achieve eradication of EDG in cases where surgery is not amenable. However, further recommendations to guide treatment remain warranted.