High-density lipoprotein (HDL) particle size and concentration changes in septic shock patients.
Sébastien TanakaDévy DialloSandrine DelboscClaire GenèveNathalie ZappellaJennyfer Yong-SangJessica PatcheAnatole HarroisSophie HamadaErick DenamurPhilippe MontraversJacques DuranteauOlivier MeilhacPublished in: Annals of intensive care (2019)
Our results emphasize that HDL levels are dramatically decreased in the acute phase of septic shock and that there is a shift toward large HDL particles, which may reflect a major dysfunction of these lipoproteins. Further mechanistic studies are required to explore this shift observed during sepsis.