Selective Inhibition of PI3K Isoforms in Brain Tumors Suppresses Tumor Growth by Increasing Radiosensitivity.

Mi Youn Seol Seo Hee Choi Ik Jae Lee Hyung Soon Park Hye Ryun Kim Sang-Kyum Kim Hong In Yoon

Published in: Yonsei medical journal (2023)

This study verified that PI3K-α isoform inhibition improves radiosensitivity, resulting in tumor growth suppression and extended survival in GBM mice.

Keyphrases

signaling pathway
high fat diet induced
type diabetes
metabolic syndrome
insulin resistance