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The incidence and risk factors of low anterior resection syndrome (LARS) after sphincter-preserving surgery of rectal cancer: a systematic review and meta-analysis.

Rui SunZiyi DaiYin ZhangJunyang LuYuelun ZhangYi Xiao
Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2021)
The incidence of major LARS after sphincter-preserving surgery is relatively high. Neoadjuvant radiotherapy, TME, anastomostic leak, and diverting stoma are major risk factors. No significant differences in postoperative anorectal functions were observed between transanal and laparoscopic TME. Pouch reconstruction was not found to be significantly beneficial to anorectal functions in long term.
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