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DNA methylation entropy as a measure of stem cell replication and aging.

Himani VaidyaHye Seon JeongKelsey KeithShinji MaegawaGennaro CalendoJozef MadzoJaroslav JelinekJean-Pierre J Issa
Published in: Genome biology (2023)
These data have implications for the mechanisms of tissue-specific functional declines with aging and for the development of DNA-methylation-based biological clocks.
Keyphrases
  • dna methylation
  • stem cells
  • genome wide
  • gene expression
  • electronic health record
  • big data
  • copy number
  • bone marrow
  • cell therapy