DNA methylation entropy as a measure of stem cell replication and aging.

Himani VaidyaHye Seon JeongKelsey KeithShinji MaegawaGennaro CalendoJozef MadzoJaroslav JelinekJean-Pierre J Issa

Published in: Genome biology (2023)

These data have implications for the mechanisms of tissue-specific functional declines with aging and for the development of DNA-methylation-based biological clocks.

Keyphrases

dna methylation
stem cells
genome wide
gene expression
electronic health record
big data
copy number
bone marrow
cell therapy