Control diet in a high-fat diet study in mice: Regular chow and purified low-fat diet have similar effects on phenotypic, metabolic, and behavioral outcomes.

Camila P Almeida-SuhettJonathan M ScottAlice GrahamYifan ChenPatricia A Deuster

Published in: Nutritional neuroscience (2017)

Our data demonstrate that young mice develop similar phenotypic, metabolic, and behavioral profiles when fed SD vs. LFD. The two diets may thus be equally appropriate as controls for an HFD, although some studies may want to consider differences in effects on cholesterol levels.

Keyphrases

high fat diet
adipose tissue
insulin resistance
high fat diet induced
weight loss
physical activity
electronic health record
metabolic syndrome
type diabetes
skeletal muscle
wild type
big data
low density lipoprotein