Anabolic actions of parathyroid hormone in a hypophosphatasia mouse model.
Amy J KohHwa Kyung NamMegan N MichalskiJustin DoLaurie K MccauleyNan E HatchPublished in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2022)
mice but did not alter the skull phenotype. These data suggest that PTH can have long bone anabolic activity in the absence of TNAP, and that PTH may have therapeutic value for individuals with hypophosphatasia-associated osteoporosis.