Radiologist Checklist for Selecting Patients to Undergo PIPAC (Pressurized IntraPeritoneal Aerosol Chemotherapy).
Elena RodolfinoMargo' Di MarcoAlessia IlotRoberto IezziBenedetta GuiGiacomo AvesaniCamilla PanicoAntonia StrippoliAndrea Di GiorgioFabio PacelliRiccardo ManfrediPublished in: Life (Basel, Switzerland) (2021)
Peritoneal carcinomatosis frequently occurs in advanced gastrointestinal and gynecological cancers. As factors such as poor drug uptake and distribution cause chemotherapy to be less effective, alternative therapies have been explored. Introduced in 2013, PIPAC (pressurized intraperitoneal aerosol chemotherapy) uses aerosolized chemotherapeutics sprayed into the patient's peritoneal cavity using a laparoscopic approach. Despite the literature showing encouraging data regarding the tolerability and efficacy of PIPAC, there is a lack of articles on the role that imaging plays in selecting patients suitable for PIPAC. The aim of this study is to combine literature-based evidence and clinical experience to provide information able to support training radiologists, as well as experienced radiologists interested in innovative therapies.
Keyphrases
- end stage renal disease
- newly diagnosed
- ejection fraction
- systematic review
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- artificial intelligence
- locally advanced
- squamous cell carcinoma
- machine learning
- clinical trial
- electronic health record
- big data
- robot assisted
- radiation therapy
- health information
- patient reported
- water soluble
- virtual reality