Prevalence of mosaicism in uncultured chorionic villus samples after chromosomal microarray and clinical outcome in pregnancies affected by confined placental mosaicism.

Ida Charlotte Bay LundNaja BecherRikke ChristensenOlav B PetersenEllen H SteffensenElse Marie VestergaardIda Vogel

Published in: Prenatal diagnosis (2019)

Prevalence of mosaicism in CVS samples is higher after CMA on uncultured tissue than after conventional karyotyping on cultured tissue. The risk of TFM is equally high in cases of mosaicism for CNVs and whole chromosomes.

Keyphrases

risk factors
preterm birth
copy number
gene expression