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Generation of glycans depleted decellularized porcine pericardium, using digestive enzymatic supplements and enzymatic mixtures for food industry.

Lucrezia MorticelliMikhail MagdeiNegin TschalakiBjoern PetersenAxel HaverichAndres Hilfiker
Published in: Xenotransplantation (2021)
The application of these enzymatic treatments for tissue deglycosylation is totally novel, low cost, and appears to be very efficient for glycan removal. The immunogenic potential of treated tissues will be further investigated in subsequent studies, in vitro and in vivo.
Keyphrases
  • low cost
  • hydrogen peroxide
  • human health
  • gene expression
  • cell surface
  • ionic liquid
  • extracellular matrix
  • nitric oxide
  • risk assessment
  • newly diagnosed
  • tissue engineering
  • single molecule
  • high speed