Generation of glycans depleted decellularized porcine pericardium, using digestive enzymatic supplements and enzymatic mixtures for food industry.
Lucrezia MorticelliMikhail MagdeiNegin TschalakiBjoern PetersenAxel HaverichAndres HilfikerPublished in: Xenotransplantation (2021)
The application of these enzymatic treatments for tissue deglycosylation is totally novel, low cost, and appears to be very efficient for glycan removal. The immunogenic potential of treated tissues will be further investigated in subsequent studies, in vitro and in vivo.