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A DNA kinetics competition strategy of hybridization chain reaction for molecular information processing circuit construction.

Weiyang TangQichen HuangZhenjie YangQiwei ZhengLihong WangJunmin ZhangLiang ChenXuechang ZhouYizhen LiuJiming Hu
Published in: Chemical communications (Cambridge, England) (2018)
Herein we propose a hybridization chain reaction based kinetics competition strategy able to recognize the combination/sequence of input signals. Further, a DNA priority encoder and a keypad lock were constructed. This strategy allowed us to develop a one-pot assay that can automatically and smartly respond to multiple inputs.
Keyphrases
  • single molecule
  • nucleic acid
  • healthcare
  • high throughput
  • circulating tumor
  • cell free
  • health information
  • aqueous solution
  • amino acid