A DNA kinetics competition strategy of hybridization chain reaction for molecular information processing circuit construction.
Weiyang TangQichen HuangZhenjie YangQiwei ZhengLihong WangJunmin ZhangLiang ChenXuechang ZhouYizhen LiuJiming HuPublished in: Chemical communications (Cambridge, England) (2018)
Herein we propose a hybridization chain reaction based kinetics competition strategy able to recognize the combination/sequence of input signals. Further, a DNA priority encoder and a keypad lock were constructed. This strategy allowed us to develop a one-pot assay that can automatically and smartly respond to multiple inputs.