Site Specific Preparation of N-Glycosylated Peptides: Thioamide-Directed Activation of Aspartate.

Published in: Angewandte Chemie (International ed. in English) (2022)

A site-specific method for the preparation of N-glycosylated peptides is described. Incorporation of a peptide backbone thioamide linkage adjacent to an Asp residue facilitates a Ag<sup>I</sup> -promoted, site-specific conversion to N-glycosylated Asn residues in peptides.

Keyphrases

amino acid
molecularly imprinted
gene expression
hiv infected
hiv testing
visible light
liquid chromatography