Comparison of Large, Medium, and Small Solid Tumor Gene Panels for Detection of Clinically Actionable Mutations in Cancer.
Eric VailJianbo SongJing XuJoseph S FryeJong Taek KimAndy PaoRhona SchreckAngela S AguiluzWenjuan ZhangSerhan AlkanAlain MitaMonica MitaRobert A FiglinDavid M EngmanJean R LopateguiPublished in: Targeted oncology (2021)
The results demonstrate that a carefully designed medium size gene panel is as effective as a large panel for the detection of clinically actionable variants and can be run by most molecular pathology laboratories.