Detection of circulating highly expanded T-cell clones in at-risk individuals for rheumatoid arthritis before the clinical onset of the disease.
Céline LamacchiaZuleika Calderin SolletDelphine Sophie CourvoisierDenis MonginGaby PalmerOliva StuderCem GabayJean VillardStéphane BuhlerAxel FinckhPublished in: Rheumatology (Oxford, England) (2021)
HEC were detected in the peripheral blood before the clinical onset of RA, in particular in the later pre-clinical phase of RA development, and their presence increased over time.