Normal volumetric and T1 relaxation time values at 1.5 T in segmented pediatric brain MRI using a MP2RAGE acquisition.

Baptiste MorelGian Franco PireddaJean-Philippe CottierClovis TauberChristophe DestrieuxTom HilbertDominique SirinelliJean-Philippe ThiranBénédicte MaréchalTobias Kober

Published in: European radiology (2020)

• The 3D MP2RAGE sequence provided a reliable quantitative assessment of brain volumes and T1 relaxation times during childhood. • An age-dependent model of normal brain maturation was established. • The normative ranges enable an objective comparison to a normal cohort, which can be useful to further understand, describe, and identify neurodevelopmental disorders in children.

Keyphrases

resting state
white matter
functional connectivity
young adults
cerebral ischemia
magnetic resonance imaging
single molecule
multiple sclerosis
computed tomography
brain injury
childhood cancer
diffusion weighted imaging
subarachnoid hemorrhage
congenital heart disease