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Carbapenemase-producing Enterobacterales in solid organ transplantation: Tip of the iceberg?

Kyle C MolinaValida BajrovicRobert A Bonomo
Published in: Transplant infectious disease : an official journal of the Transplantation Society (2022)
A liver transplant recipient developed a urinary tract infection with Citrobacter freundii complex and Klebsiella aerogenes, both producing dual carbapenemases (KPC-3/NDM-1). Whole-genome sequencing suggested plasmid transfer between organisms. Silent plasmid transmission highlights emergent threats to infection prevention, with implications for screening and antimicrobial stewardship.
Keyphrases
  • klebsiella pneumoniae
  • escherichia coli
  • urinary tract infection
  • multidrug resistant
  • crispr cas
  • gram negative
  • drug resistant
  • acinetobacter baumannii
  • cell therapy
  • bone marrow
  • pseudomonas aeruginosa