EV-miRome-wide profiling uncovers miR-320c for detecting metastatic colorectal cancer and monitoring the therapeutic response.
Chan-Keng YangHung-Chih HsuYu-Hao LiuWen-Sy TsaiChung-Pei MaYi-Tung ChenBertrand Chin-Ming TanYing-Yu LaiIan Yi-Feng ChangChi YangChia-Yu YangJau-Song YuHsuan LiuPublished in: Cellular oncology (Dordrecht) (2022)
Our clinically-oriented delineation of the mCRC-associated circulating EV-miRomes systematically revealed the functional significance of these liquid biopsy markers and further strengthen their translational potential in mCRC therapeutic monitoring.