Ultra-high-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight mass spectrometry and molecular networking analysis to investigate the chemodiversity of bioactive extracts of Annona jahnii Saff. fungi from the Brazilian Amazon.
Luciana Araújo XavierLetícia Maciel do Nascimento OdilairGilmara Prado de SousaEdineide Cristina A SouzaEduardo Jorge PilauCarla PortoAntônia Queiroz Lima de SouzaAfonso Duarte Leão de SouzaAdriana FlachLuiz Antonio M A da CostaPublished in: Rapid communications in mass spectrometry : RCM (2022)
The use of UHPLC/ESI-MS/MS data combined with MN proved useful in the dereplication of bioactive molecules of complex extracts that are still unexplored. These initial investigations should significantly assist in further research and increase the efficiency and speed in the discovery of new sources of secondary metabolites and new natural products.
Keyphrases
- ms ms
- ultra high performance liquid chromatography
- tandem mass spectrometry
- high performance liquid chromatography
- simultaneous determination
- liquid chromatography
- liquid chromatography tandem mass spectrometry
- gas chromatography
- high resolution mass spectrometry
- mass spectrometry
- small molecule
- electronic health record
- high resolution
- high throughput
- drinking water
- big data
- data analysis
- machine learning
- ionic liquid
- tissue engineering
- single cell