The clinical impact of estimating low-density lipoprotein cholesterol (LDL-C) using different equations in the general population.
Reyna LamSheila M ManemannKristina E SeehusenAlan T RemaleyJennifer L St SauverRuoxiang JiangJill M KillianMaureen SampsonJeffrey W MeeusenPaul A DeckerVéronique L RogerPaul Y TakahashiNicholas B LarsonSuzette J BielinskiPublished in: Lipids in health and disease (2024)
Discordance at clinically significant LDL-C cutpoints in both the general population and high-risk subgroups were observed across the three equations. These results show that using different methods of LDL-C calculation or switching between different methods could have clinical implications for many patients.