Increased Serum Interleukin-6 and Tumor Necrosis Factor Alpha Levels in Fabry Disease: Correlation with Disease Burden.
Nilton Salles Rosa NetoJudith Campos de Barros BentoValéria de Falco CaparboRosa Maria Rodrigues PereiraPublished in: Clinics (Sao Paulo, Brazil) (2021)
FD was associated with elevated serum levels of IL-6 and TNF-α in this cohort. The FD patients treated with ERT, particularly, women, exhibited higher levels of serum IL-6 and TNF-α than those not treated with ERT; the serum IL-6 and TNF-α levels were correlated with the MSSI scores reflecting greater disease burden.