Outcomes following proton therapy for Ewing sarcoma of the cranium and skull base.
Shivam M KharodDaniel J IndelicatoRonny L RotondoRaymond B Mailhot VegaHaruka UezonoChristopher G MorrisScott BradfieldEric S SandlerJulie A BradleyPublished in: Pediatric blood & cancer (2019)
Proton therapy is associated with a favorable therapeutic ratio in children with large Ewing tumors of the cranium and skull base. Despite its high conformality, we observed excellent local control and no marginal recurrences. Treatment dosimetry predicts limited long-term neurocognitive and neuroendocrine side effects.