Trial of a Preferential Phosphodiesterase 4B Inhibitor for Idiopathic Pulmonary Fibrosis.
Luca RicheldiArata AzumaVincent CottinChristian HesslingerSusanne StowasserClaudia ValenzuelaMarlies S WijsenbeekDonald F ZozFlorian VossToby M Mahernull nullPublished in: The New England journal of medicine (2022)
In this placebo-controlled trial, treatment with BI 1015550, either alone or with background use of an antifibrotic agent, prevented a decrease in lung function in patients with idiopathic pulmonary fibrosis. (Funded by Boehringer Ingelheim; 1305-0013 ClinicalTrials.gov number, NCT04419506.).