Spatial profiling technologies and applications for brain cancers.
Priyakshi Kalita-de CroftHabib Sadeghi RadHarry GasperKenneth J O'ByrneSunil R LakhaniChamindie PunyadeeraPublished in: Expert review of molecular diagnostics (2021)
Brain tumors are often resistant to treatment, and display both an immunosuppressive and heterogeneous tumor microenvironment. Next-generation imaging and multi-omics technologies are providing a tool for intricately characterizing their tissue biology. This information will aid in the design of effective therapies and begin to provide an understanding of therapy resistance.