The pregnancy hormone human chorionic gonadotropin differentially regulates plasmacytoid and myeloid blood dendritic cell subsets.

Karoline SaussStefanie EhrentrautAna Claudia ZenclussenAnne Schumacher

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2018)

Our data propose that hCG is not a key regulator of cellular alterations within PBDCs. However, under inflammatory conditions, hCG seems to keep the delicate balance between PDC and MDC and retains a tolerogenic MDC1 profile and this may contribute to tolerance maintenance.

Keyphrases

dendritic cells
endothelial cells
regulatory t cells
immune response
electronic health record
preterm birth
induced pluripotent stem cells
oxidative stress
peripheral blood
big data
pregnancy outcomes
bone marrow
acute myeloid leukemia