An International Cohort Study of Prognosis Associated With Pathologically Complete Response Following Neoadjuvant Chemotherapy Versus Chemoradiotherapy of Surgical Treated Esophageal Adenocarcinoma.
Jonathan Cools-LartigueSheraz Rehan MarkarCarmen MuellerWayne HofstetterMagnus NilssonIlkka IlonenHenna SoderstromJari RasanenSuzanne GisbertzGeorge B HannaJessie ElliottJohn ReynoldsAaron KisielEwen GriffithsMark Van Berge HenegouwenLorenzo FerriPublished in: Annals of surgery (2022)
The results of this international cohort study show that the prognosis of pCR following different neoadjuvant regimes differs, bringing into question the validity of this measure as an oncological surrogate when comparing neoadjuvant treatment schemes for esophageal adenocarcinoma.