Lycopene Alleviates Titanium Dioxide Nanoparticle-Induced Testicular Toxicity by Inhibiting Oxidative Stress and Apoptosis in Mice.
Xiaojia MengLi LiHongmei AnYaxin DengChunmei LingTianjiao LuGuangling SongYan WangPublished in: Biological trace element research (2021)
LYC could ameliorate TiO2 NPs-induced testicular damage via inhibiting oxidative stress and apoptosis, which could be used to alleviate the testicular toxicity associated with TiO2 NPs intake.
Keyphrases
- oxidative stress
- diabetic rats
- dna damage
- ischemia reperfusion injury
- induced apoptosis
- germ cell
- high glucose
- signaling pathway
- endoplasmic reticulum stress
- type diabetes
- drug induced
- oxide nanoparticles
- adipose tissue
- heat shock
- weight gain
- metabolic syndrome
- skeletal muscle
- high fat diet induced
- mouse model
- wild type
- heat shock protein
- weight loss