Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug.

Lisa SandersonMarcelo Alves Da SilvaGayathri N SekharRachel C BrownHollie Burrell-SawardMehmet Fidanboylu Bo Liu Lea Ann Dailey Cécile A Dreiss Christian D LorenzMark ChristieShanta Jean PersaudVanessa YardleySimon L CroftMargarita Valero Sarah Ann Thomas

Published in: PLoS neglected tropical diseases (2021)

These results are relevant to further developing block-copolymers as nanocarriers, improving BBB drug penetration and understanding the side effects of pentamidine.

Keyphrases

adverse drug
drug delivery
blood brain barrier
drug induced
quality improvement
drug release
electronic health record