Lymphoblast transcriptome analysis in 22q11.2 deletion syndrome individuals with schizophrenia-spectrum disorder.

Elena MichaelovskyMiri CarmelDoron GothelfAbraham Weizman

Published in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2024)

Candidate pathways and upstream regulators may serve as novel biomarkers and treatment targets for SZ. Future transcriptome studies, including larger samples and proteomic analysis, are needed to substantiate our findings.

Keyphrases

spectrum disorder
bipolar disorder
genome wide
rna seq
single cell
current status
case report
combination therapy
dna methylation
case control
replacement therapy