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Dodging Endosomes: Effective Cytosolic Antibody Delivery.

Dennis W P M Löwik
Published in: Chembiochem : a European journal of chemical biology (2017)
On the inside: New methodologies for delivering antibodies right into the cytosol of cells either directly across the plasma membrane or by allowing the antibody to escape from endosomes have been proposed recently by the Cardoso/Hackenberger and Futaki groups, respectively.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • endoplasmic reticulum stress
  • cell death
  • signaling pathway