Losartan reverses impaired osseointegration in spontaneously hypertensive rats.
Gabriel Mulinari-SantosFábio Roberto de Souza BatistaFranziska KirchwegerStefan TanglReinhard GruberRoberta OkamotoPublished in: Clinical oral implants research (2018)
The data presented suggest that the angiotensin II receptor antagonist losartan increases the medullary parameters of osseointegration in a tibia model of spontaneously hypertensive rats. Considering the study limitations, understanding the impact of hypertension and the respective drugs on osseointegration requires further research.