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CRITICAL ANALYSIS OF ANTI-TNF USE IN THE ERA OF NEW BIOLOGICAL AGENTS IN INFLAMMATORY BOWEL DISEASE.

Camila Cunha Gonzaga LimaNatália Souza Freitas QueirozCarlos Walter Sobrado JuniorGustavo Luís Rodela SilvaSergio Carlos Nahas
Published in: Arquivos de gastroenterologia (2021)
Biological therapy remains the cornerstone in the treatment of IBD. In the absence of head-to-head comparisons, the choice of the biological agent may be challenging and should take into account several variables. Anti-TNF agents should be considered as first line therapy in specific scenarios such as acute severe ulcerative colitis, fistulizing Crohn's disease and extra-intestinal manifestations of IBD, given the strong body of evidence supporting its efficacy and safety in these situations.
Keyphrases
  • ulcerative colitis
  • rheumatoid arthritis
  • liver failure
  • climate change
  • drug induced
  • respiratory failure
  • hepatitis b virus
  • bone marrow
  • decision making
  • acute respiratory distress syndrome