Brain amyloid, cortical thickness, and changes in activities of daily living.
Maria VassilakiJeremiah A AakreWalter K KremersTimothy G LesnickMichelle M MielkeYonas E GedaMary M MachuldaDavid S KnopmanLesley ButlerMartin TraberPrashanthi VemuriVal J LoweClifford R JackRosebud O RobertsRonald C PetersenPublished in: Annals of clinical and translational neurology (2020)
The longitudinal increase in functional limitations is greater for individuals with abnormal neuroimaging biomarkers, especially for those with both elevated brain amyloid and neurodegeneration.